Vitamin D deficiency and recurrent miscarriages

In recent years, research has led to the discovery that vitamin D deficiency in pregnant women is associated with an increased risk of obstetric complications , such as pre-eclampsia, bacterial vaginosis with associated preterm delivery, gestational diabetes, and low birth weight babies. .

These studies have recently been joined by others with the aim of evaluating the possible correlation between low vitamin D values ​​and the risk of recurring spontaneous abortions .

The most recent studies on vitamin D

A research was conducted by the Department of Microbiology and Immunology at the Chicago Medical School Rosalind Franklin University of Medicine and Science.

We enrolled 133 women among those who had at least 3 consecutive spontaneous abortions within 20 weeks of gestation. 63 of 133 women (47.4%) had vitamin D levels < 30 ng/mL (minimal normal level).

Furthermore, a further study was published in the European Journal of Clinical Nutrition in which 60 women were compared on the one hand, 30 of whom were pregnant with a baby beyond the first trimester and 30 who had spontaneously terminated a pregnancy between 7 and 9 weeks of gestation.

Another group of 60 women included 30 with a history of completed pregnancy and 30 with a history of miscarriage within the first 90 days.

Again, women who had just suffered a miscarriage or had a prior history of miscarriage had, for the most part, lower serum vitamin D levels than their current or completed pregnancy correspondents. .

Should vitamin D be supplemented when deficient?

In the light of these (and many other similar) studies, therefore, the scientific community recommends an assessment of the level of vitamin D in women with recurrent miscarriages and, in case of insufficiency (levels < 30 ng/ml) or deficiency (levels < 10 ng/ml) recommends evaluating the possibility of integration.