Prenatal diagnostic tests by week of pregnancy

All couples have the right to be informed about the possibilities of prenatal diagnosis for the detection of any fetal abnormalities. And this is regardless of the age of the mother.

Prenatal diagnostic tests by week of pregnancy. During the first visit , the gynecologist should in fact inform the future parents about the various techniques available, invasive or non-invasive, the risks and benefits, so that the couple can face an informed choice.

Non-invasive prenatal diagnostic tests by week of pregnancy

Non-invasive tests are defined as screening tests that do not put the pregnancy at risk during their execution.

All these tests do not provide certain data but a probability.

Nuchal translucency : from 11+0 to 13+6 weeks of pregnancy

Combined Test (Nuchal Translucency + Bi-test ):

• Nuchal translucency: from 11+4 to 13+6
• Blood sampling for the Bi-test: from 9+0 to 13+6

Integrated Test : Combined Test + further blood sampling ( Tri-test ) at 15-18 weeks.

Fetal DNA test : from 10+0 weeks of pregnancy. There are various types of tests (such as PrenatalSafe, Nativa, Harmony, Aurora, Neobona or Vera test) each with its own sensitivity and specificity.

Morphological Ultrasound :  from 19+0 to 21+0 weeks of pregnancy

invasive tests

The following tests provide a certain result, they are diagnostic tests, which however are accompanied by a small percentage of risk. CVS has a miscarriage risk of around 1%, while amniocentesis around 0.5-1%.

CVS : from 11+0 to 13 weeks of pregnancy

Amniocentesis : from 15+1 to 18 weeks of pregnancy

On the samples taken with these techniques (chorionic villi or amniotic fluid), in addition to the analysis of the karyotype, a genetic analysis of the fetal DNA can be combined. For example, the PrenatalScreen test allows an analysis of over 1000 genetic diseases to be performed on the fetus.