Conception

Inositol helps to ovulate again and get pregnant

Polycystic ovarian syndrome, or PCOS, is a hormonal disorder that can cause symptoms such as menstrual irregularities, infertility, acne and weight gain. It also increases your risk of developing serious health conditions like diabetes and some heart diseases. Research suggests that an inositol supplement, specifically myoinositol, may help improve these conditions.

We hear very often about medical prescriptions of Inofolic, Inofolic Plus, Inofert and Chirifol. All these drugs have inositol as their main protagonist.

What is inositol and what is it for?

Inositol  is a carbocyclic polyol whose most important form in nature is myoinositol (cis-1,2,3,5-trans-4,6  cyclohexanesol).

Myo-inositol, as synthesized by the human body, cannot properly be considered a vitamin even if it is generally indicated as belonging to the vitamins of the B complex (B7).

Inofolic, Inofolic Plus, Inofert all contain myo-inositol (2 grams) while Chirifol contains chiro-inositol (250 mg). All four also have folic acid and Inofolic Plus melatonin.

They are generally prescribed to women who have fertility problems such as polycystosis of the ovary.

Polycystic ovary syndrome , or PCOS  , is a hormonal disorder that can cause symptoms such as menstrual irregularities, infertility, acne and weight gain . It also increases your risk of developing serious health conditions like diabetes and some heart diseases.

Research suggests that a myo-inositol supplement may help improve these conditions .

Several studies have been done in this regard, comparing women who took myoinositol and women who took a plecebus and the results demonstrated the effectiveness of this substance in improving women’s fertility.

Inositol has very low costs (even if the price of the 4 supplements in the pharmacy does not seem …) and substantially non-existent side effects (even if there are no studies that can definitively confirm it).

How does inositol work?

Studies have confirmed that women with micropolycystic ovaries also often suffer from insulin resistance linked to a defect in the insulin receptor present on the cells, inositol-phosphoglycan. Administering myo-inositol also increases the availability of the receptor. In this way the cells are stimulated to start “working” again.

However, the effects are multiple, such as for example on the regulation of sugar metabolism, on the modulation of the signals of the nervous system that regulate serotonin levels and on the lowering of cholesterol levels in the blood.

But what interests us more directly are the effects on fertility.

In fact, myo-inositol acts by regulating the menstrual cycle and therefore allowing for correct ovulation, a necessary condition for trying to get pregnant. At the same time it improves all the other symptoms that usually accompany ovarian polycystosis such as improvement in blood sugar, hirsutism (excessive hair growth is another symptom of PCOS), improves blood pressure and triglyceride levels.

All situations that contribute to a general improvement of the woman’s metabolism. In some cases it also appears to have an antidepressant effect.

PCOS, insulin resistance and recurrent miscarriages

Very recent studies have shown that there is a relationship between polycystic ovary syndrome, insulin resistance and recurrent miscarriages.

Insulin resistance, which can improve thanks to the supplement of inositol, seems in fact to be one of the causes of recurrent miscarriages .

And since the side effects seem non-existent, talk to your doctor, gynecologist or endocrinologist to start the right therapy that can help you realize your desire for motherhood!

Kathryn Barlow is an OB/GYN doctor, which is the medical specialty that deals with the care of women's reproductive health, including pregnancy and childbirth.

Obstetricians provide care to women during pregnancy, labor, and delivery, while gynecologists focus on the health of the female reproductive system, including the ovaries, uterus, vagina, and breasts. OB/GYN doctors are trained to provide medical and surgical care for a wide range of conditions related to women's reproductive health.

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