Conception

Clomid and irregular cycles: is it effective?

I often get questions about clomiphene citrate and how effective it is to take. Therefore I asked Dr. Tinelli, surgeon, specialist in Obstetrics and Gynecology, for some clarifications that you find below:

Clomid (clomiphene citrate) is a drug that acts at the level of the central nervous system, in the pituitary gland, inducing a production of FSH hormone (follicle stimulating) by the pituitary gland itself with consequent ovarian development of one or more follicles.

Their oral administration and their effectiveness in relation to the low cost make them widely used drugs in young women who have irregular ovulations. Treatment ranges from 50 to 100 mg per day for 5 days.
A recent retrospective study on the use of Clomiphene citrate for the induction of ovulation in case of intrauterine insemination has shown pregnancy rates per cycle of around 5%.
Therefore, this data associated with the low cost and easy intake justifies the use of clomiphene citrate in infertile couples as a first therapeutic approach.
The risk of multiple pregnancies is comparable to that of gonadoptropins used directly (about 10%).
Last but not least, the drug must be used under the strict supervision of a specialist fertologist due to the – rare – risk of causing ovarian hyperstimulation syndrome, an insidious complication that is sometimes serious and represents a threat to the patient’s life.

Dr Kathryn Barlow

Kathryn Barlow is an OB/GYN doctor, which is the medical specialty that deals with the care of women's reproductive health, including pregnancy and childbirth.

Obstetricians provide care to women during pregnancy, labor, and delivery, while gynecologists focus on the health of the female reproductive system, including the ovaries, uterus, vagina, and breasts. OB/GYN doctors are trained to provide medical and surgical care for a wide range of conditions related to women's reproductive health.

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