A child at 44, is it possible? If yes how? The geneticist answers

Howdy

I am writing to her because for weeks my partner and I have been trying to have a child but nothing (I am 44 years old, I am the mother of a 22-year-old daughter and a 13-year-old son born with natural birth and without problems). In January I started taking the folina and finally on February 14th I found out I was expecting a baby. I make the first visit and the gynaecologist makes me a little scared maybe because she had seen something wrong. He makes me do the tests that were perfect, but at the check my baby’s heart was no longer beating. It was terrible. On March 19 I did the scraping and today I have some slight brownish loss, hemorrhage I have never had. The doctors all told me to go back immediately, I’m recovering the folina but I’m afraid it could happen again. I am afraid that he could be born with some genetic problem or have diabetes (my father
had mellitus) so I would opt for assisted reproduction. In this regard, I want to know where it can be done. I would like to know cme works if you pay and how much it costs. We want a
child so much. Thank you.

Dear reader,
what happened to you is a normal feedback at 44 years of age. Unfortunately, oocytes “age” accumulate a series of “errors” that are then reflected in miscarriages or
failed embryo implants.
I believe that her reproductive chances are low and that the chances, at her age, are 3:
1) natural fertilization, since she still appears fertile, and then prenatal diagnosis (chorionic villus sampling) at 11 weeks of pregnancy to verify the normality of
fetal chromosomes. At 44, with preserved fertility, this is the option that gives her the most likelihood.
2) assisted fertilization (ART) but only if accompanied by preimplantation diagnosis for the analysis of embryonic chromosomes. PMA alone does not increase its chances of
success, but it is a sine qua non for performing preimplantation diagnosis, which could instead increase its chances. However, it is possible that the number of embryos produced is very low and that, after analysis, there are no healthy embryos
to be transferred. In addition, the method is entirely paid. The many public centers that
perform PMA in Italy do not perform pre-implantation diagnosis, available only in private centers. For the age limit it will be necessary to inquire, since this limit is set at regional level (in Veneto, for example, there is no age limit).
3) egg donation, to be carried out abroad. This method, which involves the acceptance of oocyte from anonymous donor, at her age offers the greatest
chance of pregnancy, as the donors are all very young.